You could, but you would see alot of performance loss. The 2-stroke motor uses the "exhaust chambers" to harness the power of a 2-stroke... that's where you get the well known 2 stroke power band... from the pipe or "exhaust chamber". if you notice 2 stroke pipes come in different i width and size. That's because they serve different purposes... depending on what type of performance you want. Short fat pipes produce more low end power and longer pipes produce more top end power.

your motor would run, but your not going to harness the performance like you would if it had a big fatty pipe and silencer on it.